2. International SCI Journal

Murthy HN, M. Georgiev, SY. Park, VS. Dandin, KY. Paek. 2015.

The safety assessment of food ingredients derived from plant cell, tissue and organ cultures: A review. Food Chemistry.176:426-432

Yu GJ, Choi IW, Kim GY, Kim BW, Park C, Hong SH, Moon SK, Cha HJ, Chang YC, Paek KY, Kim WJ, Choi YH. 2015.

Anti-inflammatory potential of saponins derived from cultured wild ginseong roots in lipopolysaccharide-stimulated RAW 264.7 macrophages. Int'l J Molecular Medicine.35:1698-2015. (염증치료)

Thanh NT, HN. Murthy, KY. Paek. 2014.

Optimization of ginseong cell culture in airlift bioreactors and developing the large scale production system.

Industrial Crops and Products. 60:343-348.

Murthy HN, EJ Lee, KY Paek. 2014.

Production of secondary metabolites from cell and organ cultures: strategies and approaches for biomass improvement and metabolite accumulation.

Plant Cell Tiss Organ Cult.118:1-16.

Murthy HN, VS Dandin, EJ Lee, KY Paek. 2014.

Efficacy of ginseong adventitious root extract on hyperglycemia in streptozotocin -induced diabetic rats.

Journal of Ethnopharmacology.153:917-921. (혈당조절)

Murthy HN, V Dandin, KY Paek. 2014.

Hepatoprotective activity of ginsenosides from Panax ginseong adventitiious roots against carbob tetrachloride treated hapatic injuryb in rats.

Journal of Ethnopharmacology.158:442-446. (간보호)

Sivakumar G, F Medina-Bolivar, JO Lay, MC Dolan, J Condori, SK Grubbs, SM. Wright, MA Baque, EJ Lee, KY Paek. 2011.

Bioprocess and bioreactor: Next generation technology for production of potential plant-based antidiabetic and antioxidant molecules .

Current Medicinal Chemistry.18(1)79-90. (항당뇨)

Tewari RK and KY Paek. 2011.

Salicylic acid-induced nitric oxide and ROS generation stimulate ginsenoside accumulation in Panax ginseng roots.

J. Plant Growth Regul. 30:396-404.

Dewir YH, D Chakrabarthy, CH Wu, EJ Hahn, WK Jeon, KY Paek. 2010.

Influences of polyunsaturated fatty acid(PUFAs) on growth and secondary metabolite accumulation in Panax ginseng C.A. Meyer adventitious roots cultured in air-lift bioreactors. South African J Botany.76:354-358.

Murthy HN, EJ Hahn, and JJ Zhong, KY Paek. 2009.

Large Scale Culture of Ginseng Adventitious Roots for Production of Ginsenosides . Adv Biochem Engin/Biotechnol.113:151-176.

Wu CH, EV Popova, EJ Hahn, KY Paek. 2009.

Linoleic and a-linolenic fatty acids affect biomass and secondary metabolite production and nutritive properties of Panax ginseng adventitious roots cultured in bioreactors. Biochemical Engineering Journal.47:109-115.

Kim TH, SH Jeon, EJ Hahn, JK Park, NY Youn, HR Lee, KY Paek. 2009.

Effects of tissue-cultured mountain ginseng(Panax ginseng C.A. Meyer) extract on male patients with erectile dysfunction .

Asian J. Andrology.11:356-361. (발기부전 개선)

Choi HW, DH Koo, KH Bang, NS Seong, JW Bang, KY Paek,. 2009.

FISH and GISH analysis of the genomic relationships among Panax species. Genes & Genomics. 31:99-105.

RK Tewari, SH Kim, EJ Hahn, KY Paek. 2008.

Involvement of nitric oxide-induced NADPH oxidase in adventitious root growth and antioxidant defense in Panax ginseng. Plant Biotechnol Rep.2:113-122.

Murthy HN, EJ Hahn and KY Paek. 2008.

Adventitious Roots and Secondary Metabolism. Chinese Journal of Biotechnology. 24(5)711-716.

Ali MB, YH Dewir, EJ Hahn and KY Paek. 2008.

Effect of carbon dioxide on antioxidant enzymes and ginsenoside production in root suspension cultures of Panax ginseng.

Environmental and Experimental Botany.63: 297-304.

Tewari RK, EJ Hahn and KY Paek. 2008.

Modulation of copper toxicity-induced oxidative damage by nitric oxide supply in the adventitious roots of Panax ginseng. Plant Cell Reports. 27(1) 171-181.

Tewari RK, EJ Hahn and KY Paek. 2008.

Function of nitric oxide and superoxide anion in the adventitious root development and antioxidant defence in Panax ginseng. Plant Cell Reports. 27(3) 563-573.

Jeong CS, HN Murthy, EJ Hahn and KY Paek. 2008.

Improved production of ginsenosides in suspension cultures of ginseng by medium replenishment strategy.

Journal of Bioscience and Bioengineering.105(3) 288-291.

Jeon WK, BK Yoo, YE Kim, SO Park, EJ Hahn, KY Paek, and BS Ko. 2008.

Anti-platelet Activity of Tissue-cultured Mountain Ginseng Adventitious Roots in Human Whole Blood .

Food Science and Biotechnology.17(6) 1197-1202. (항혈소판 활성)

Kim SJ, HN Murthy, EJ Hahn, HL Lee and KY Paek. 2008.

Effect of processing methods on the concentrations of bioactive components of ginseng (Panax ginseng C.A. Meyer) adventitious roots.

LWT-Food Science and Technology. 41(6) 959-964.

Wu CH, HN Murthy, EJ Hahn and KY Paek. 2008.

Establishment of adventitious root co-culture of Ginseng and Echinacea for the production of secondary metabolites.

Acta Physiologiae Plantarum. 30(6) 891-896.

Jeong CS, HN Murthy, HL Lee, EJ Hahn and KY Paek. 2008.

Inoculum size and auxin concentration influence the growth of adventitious roots and accumulation of ginsenosides in suspension cultures of ginseng(Panax ginseng C.A. Meyer).

Acta Physiologiae Plantarum. 31(1) 219-222.

Ali MB, EJ Hahn and KY Paek. 2007.

Methyl jasmonate and salicylic acid induced oxidative stress and accumulation of penolics in Panax ginseng bioreactor root suspension cultures.

Molecules. 12(3):607-621.

Kim SJ, HN Murthy, EJ Hahn, HL Lee and KY Paek. 2007.

Parameters affecting the extraction of ginsenosides from the adventitious roots of ginseng(Panax ginseng C.A. Meyer).

Separation and Purification Technology. 56:401-406.

Kim YS, EC Yeung, EJ Hahn and KY Paek. 2007.

Combined effects of phytohormone, indole-3-butyric acid, and methyl jasmonate on root growth and ginenoside production in adventitious root cultures of Panax ginseng C.A. Meyer.

Biotechnology Letters. 29(11):1789-1792

Tewari RK, SY Lee, EJ Hahn and KY Paek. 2007.

Temporal changes in the growth, saponin content and antioxidant defence in the adventitious roots of Panax ginseng subjected to nitric oxide elicitation .

Plant Biotechnology Reports. 1(4):227-235.

Park JS, SY Hwang, WS Lee, KY Paek, BY Hwang, and K Han. 2006.

The therapeutic effect of tissue cultured root of wild Panax ginseng CA. Mayer on spermatogenic disorder.

Archibes of Pharmacal Research. 29(9):800-807. (정자형성장애 개선)

Jeong CS, D Chakrabarty, EJ Hahn, HL Lee and KY Paek. 2006.

Effects of oxygen, carbon dioxide and ethylene on growth and bioactive compound production in bioreactor culture of ginseng adventitious roots .

Biochemical Engineering Journal. 27(3):252-263

Sivakumar G., KW Yu and KY Paek. 2006.

Enhanced production of bioactive ginsenosides from adventitious roots of Panax ginseng in bioreactor culture. Journal of Horticultural Science and Biotechnology. 81(3):549-552.

Ali MB, N Singh, AM Shohael, EJ Hahn and KY Paek. 2006.

Phenolics metabolism and lignin synthesis in root suspension cultures of Panax ginseng in response to copper stress. Plant Science.171(1):147-154.

Sivakumar G., KW Yu, JS Lee, JK Kang, HL Lee, WJ Kim, and KY Paek. 2006.

Tissue cultured mountain ginseng adventitious roots TM: Safety and toxicity Evaluation. Eng. Life Sci. 6(4):1-13.

Ali MB, KW Yu, EJ Hahn and KY Paek. 2006.

Methyl jasmonate and salicylic acid elicitation induces ginsenosides accumulation, enzymatic and non-enzymatic antioxidant in suspension culture Panax ginseng roots in bioreactors. Plant Cell Reports. 25(6):613-620.

Nguyen TT, HN Murthy, KW Yu, CS Jeong, EJ Hahn and KY Paek. 2006.

Effect of oxygen supply on cell growth and saponin production in bioreactor cultures . Journal of Plant Physiology.163(12):1337-1341.

Ali MB, EJ Hahn and KY Paek. 2006.

Copper-induced changes in the growth, oxidative metabolism, and saponin production in suspension culture roots of Panax ginseng in bioreactors . Plant Cell Reports. 25(10):1122-1132.

Sivakumar G, KW Yu, EJ Hahn and KY Paek. 2005.

Optimization of organic nutrients for ginseng hairy roots production in large-scale bioreactors.

Current Science. 89(4):641-649.

Yu KW, HN Murthy, EJ Hahn and KY Paek. 2005.

Ginsenoside production by hairly root cultures of Panax ginseong : influence of temperature and light quality.

Biochemical Engineering J. 23:53-56.

Paek KY, D Chakrabarty and EJ Hahn. 2005.

Application of bioreactor systems for large scale production of horticultural and medicinal plants.

Plant Cell, tissue and Organ Culture. 81(3):287-300.

Sivakumar G, KW Yu and KY Paek. 2005.

Production of biomass and ginsenosides from adventitious roots of Panax ginseng in bioreactor cultures. Engineering In Life Sciences. 4:333-342.

Thanh NT, HN Murthy, KW Yu, EJ Hahn and KY Paek. 2005.

Methyl jasmonate elicitation enhanced synthesis of ginsenoside by cell suspension cultures of Panax ginseng in 5-l balloon type bubble bioreactors.

Applied Microbiology and Biotechnology. 67(2):197-201.

Ali MB, TT Nguyen, KW Yu, EJ Hahn, KY Paek and H L Lee. 2005.

Induction in the antioxidative systems and lipid peroxidation in suspension culture roots of Panax ginseng induced by oxygen in bioreactors.

Plant Science.169(5):833-841.

Ali MB, KW Yu, EJ Hahn and KY Paek. 2005.

Differential responses of anti-oxidants enzymes, lipoxygenase activity, ascorbate content and the production of saponins in tissue cultured root of mountain Panax ginseng C.A. Mayer and Panax quinquefolium L. in bioreactor subjected to methyl jasmonate stress.

Plant Science.169:83-92

Ali MB, EJ Hahn and KY Paek. 2005.

CO2-induced total phenolics in suspension cultures of Panax ginseng C.A. Mayer roots: role of antioxidants and enzymes.

Plant Physiology and Biochemistry. 43(5):423-502.

Yu KW, HN Murthy, CS Jeong, EJ Hahn and KY Paek. 2005.

Organic germanium stimulates the growth of ginseng adventitious roots and ginsenoside production.

Process Biochemistry. 40:2959-2961.

Kim YS, EJ Hahn, HN Murthy and KY Paek. 2004.

Adventitious root growth and ginsenoside accumulation in Panax ginseng cultures as affected by methyl jasmonate.

Biotechnology Letters. 26:1619-1622.

Kim YS, EJ Hahn, HN Murthy and KY Paek. 2004.

Effect of polyploidy induction on biomass and ginsenoside accumulations in adventitious roots of ginseng.

Journal of Plant Biology. 47(4):356-360.

Kim YS, EJ Hahn, EC Yeung and KY Paek. 2003.

Lateral root development and saponin accumulation as affected by IBA or NAA in adventitious root cultures of Panax ginseng C.A. Meyer.

In Vitro Cell Dev. Biol.-Plant. 39:245-249.

Yu KW, WY Gao, EJ Hahn and KY Paek. 2002.

Jasmonic acid improves ginsenoside accumulation in adventitious root culture of Panax ginseng C.A. Meyer.

J. Biochemical Engineering. 11:211-215.

Lian ML, D Chakrabarty and KY Paek. 2002.

Effect of plant grwoth regulators and medium composition on cell growth and saponin production during cell-suspension culture of mountain ginseng(Panax ginseng C.A. Mayer).

J. of Plant Biology.45(4):201.206

Yu Kee Won, Wen Yuan Gao, Hahn Eun Joo, Paek Kee Yoeup. 2001.

Effects of macro elements and nitrogen source on adventitious root growth and ginsenoside production in ginseng(Panax ginseng C.A. Meyer)..

J. of Plant Biology.44:(4):179-184.

Choi SM, SH Son, SR Yun, OW Kwon, JH Seon and KY Paek. 2000.

Pilot-scale culture of adventitious roots of ginseng in a bioreactor system.

Plant Cell Tissue and Organ Culture. 62:187-193.

Yu KW, Y Gao, SH Son and KY Paek. 2000.

Improvement of ginsenoside production by jasmonic acid and some other elicitors in hairy root culture of Ginseng(Panax ginseng C.A. Meyer).

In Vitro Cell Dev. Biol. Plant. 36:424-428.

3. Technical Papers and Review Articles in International Sym. Proceedings

Paek KY and EJ Hahn. 2005.

Increase of saponin contents via elicitor treatments in bioreactor culture of ginseng (Panax ginseng C.A. Meyer) adventitious roots.

Acta Hort. 679.pp. 145-148.

Yu K.W., E.J. Hahn, and K.Y. Paek. 2003.

Ginsenoside production by hairy root cultures of Panax ginseng C.A. Meyer in bioreactors.

Acta Hort. 597.pp. 237-243.

Hahn EJ, JW Choi, JH Kim and KY Paek. 2003.

The study on tissue cultured wild mountain ginseng(Panax ginseng C.A. Meyer) adventitious roots extract as a cosmetic ingredient.

Cosmetics: Where science meets dream, IFSCC Conf. Seoul, Korea. pp. 611-616.

Kim YS, D Chakrabarty, EJ Hahn and KY Paek. 2003.

Methyl jasmonate increases saponin content in bioreactor culture of ginseng(Panax ginseng C.A. Meyer) adventitious roots.

Acta Hort. 625.pp. 289-292.

Hahn EJ, KW Yu, CS Jeong and KY Paek. 2003.

Commercial scale production of bioactive compounds through large-scale bioreactor culture of Panax ginseng C.A. Meyer.

Proc. 1st Int. Cong. on Bioreactor Technology in Cell, Tissue Culture and Biomedical Applications, Tampere, Finland. pp. 30-40.

Paek KY and EJ Hahn. 2002.

Adentitious root cultures of Panax ginseng C.A. Meyer and ginsenoside production through large-scale bioreactor system.

The 9th symposium on plant biotechnology, Chungnam University, Korea. pp. 31-36.

Yu KW, EJ Hahn and KY Paek. 2001.

Effects of NH4:NO3 ratio and ionic strength on adventitious root growth and ginsenoside production in bioreactor culture of Panax ginseng C.A. Meyer.

Proc. Ⅳ IS on In Vitro Cult. ＆ Hort. Breeding. Acta Hort. 560:259-262.

4. Invited Review Articles in Monograph Textbook

Murthy HN and KY Paek. 2016.

Panax ginseong adventitious root suspension culture: Protocol for biomass production and analysis of ginsenoside by high liquid chromatography.

In: Potocols for in vitro culture and secondary metabolite analysis of aromatic and medicinal plants. S. Mohan Jain(ed.). Springer. Chapter 9. 125-139.

Murthy HN, KY Paek, SY Park, and VS Dandin . 2016.

Safety issues of food ingredients from plant cell, tissue, and organ cultures: An explication. Chapter 8. In: Food Toxicology, edited by D. Bagchi and A. Swaroop.

CRC Press.151-164.

Thanh NT, HN Murthy and KY Paek. 2014.

Ginseng cell culture for production of ginsenosides. p121-142. In; Production of biomass and bioactive comppounds using bioreactor technology.(KY Paek, HN Murthy, JJ Zhong, eds). Springer. p.121-142.

Murthy HN , VS Dandin, JJ Zhong and KY Paek. 2014.

Strategies for enhanced production of plant secondary metabolites from cell and organ cultures.

In; Production of biomass and bioactive comppounds using bioreactor technology.(KY Paek, HN Murthy, JJ Zhong, eds). Springer. p.471-508.

Tewari RK and KY Paek. 2014.

Role of nitric oxide in adventitious root development.

In; Production of biomass and bioactive comppounds using bioreactor technology.(KY Paek, HN Murthy, JJ Zhong, eds). Springer. p.429-444.

Murthy HN, YS Kim, CS Jeong, SJ Kim, JJ Zhong, KY Paek. 2014.

Production of ginsenosides from adventitious root culture of Panax ginseng.

In; Production of biomass and bioactive compounds using bioreactor technology.(KY Paek, HN Murthy, JJ. Zhong, eds). Springer. p.625-654.

Murthy HN and KY Paek. 2014.

Food ingridients from plant cell, tissue and organ cultures: Bio=safety and efficacy evaluations. In; Production of biomass and bioactive compounds using bioreactor technology.(KY Paek, HN Murthy, JJ Zhong, eds). Springer. p.655-692.

Paek KY, HN Murthy, EJ Hahn, JJ Zhong. 2009.

Large Scale Culture of Ginseng Adventitious Roots for Production of Ginsenosides. In: From bioreaction to bioseparation and bioremediation(T Scheper, JJ Zhong, FW, Bai, W Xhang, eds.). Adv Biochem Engin/Biotechnol, Springer.113:151-176.

Choi YE, YS Kim and KY Paek. 2006.

Types and Designs of Bioreactors for Hairy Root Culture.

In: SD Gupta and Y Ibaraki,(eds.) Focus on biotechnology, plant tissue culture engineering. Springer Netherlands. pp.161-172.

Choi YE, YS Kim and KY Paek. 2006.

Types and Designs of Bioreactors for Hairy Root Culture.

In: SD Gupta and Y Ibaraki,(eds.) Focus on biotechnology, plant tissue culture engineering. Springer Netherlands. pp.161-172.

Son SH and KY Paek. 2000.

Large-scale production of medicinal plant species : The application of bioreactors for production of ginseng roots. In: Development of plant-based medicines : Conservation, efficacy and safety(P.K. Saxena, ed). Kluwer Academic Publishers. pp.139-150.